The Exposed Proteomes of Brachyspira hyodysenteriae and B. pilosicoli and discusses various treatments and prevention strategies to control AIS. This review summarises the current knowledge about AIS infection caused by B. Consequently, the number of outbreaks of AIS has dramatically increased in the UK resulting in significant economic losses. Due to the large increase of bacterial resistance to antibiotic treatment, the European Union banned in 2006 the prophylactic use of antibiotics as growth promoters in livestock. During AIS, this opportunistic pathogen colonises the lower gastrointestinal (GI) tract of poultry (principally, the ileum, caeca, and colon), which can cause symptoms such as diarrhoea, reduced growth rate, and reduced egg production and quality. Claus, Sandrine P.Īvian intestinal spirochaetosis (AIS) is a common disease occurring in poultry that can be caused by Brachyspira pilosicoli, a Gram-negative bacterium of the order Spirochaetes. PMID:9508297īrachyspira pilosicoli-induced avian intestinal spirochaetosis The present data provide evidence that intestinal Serpulina-like organisms can be important as a cause of disease in guinea pigs. The organisms did not stain by an immunofluorescence technique for the detection of Serpulina hyodysenteriae. Electron microscopy demonstrated the presence of large numbers of Serpulina-like organisms adhering to the cecal mucosae of these animals.
Lesions consisted of a catarrhal or hemorrhagic inflammation of the colon and cecum (typhlitis). When larger colonies of guinea pigs were involved, the disease spread very rapidly unless treatment with ronidazole was initiated. Occasionally, they produced yellow, slimy feces or showed nervous signs, but the condition always had a fatal outcome within 24 h. All infected animals had a history of sudden death with minimal introductory clinical signs. Charlier, Gerard Haesebrouck, Freddyīetween January 1992 and December 1996, Serpulina-like bacteria were demonstrated in intestinal tract lesions from 37 of 88 guinea pigs submitted to the University of Ghent in Ghent, Belgium, for necropsy because of disease and death from different unknown causes. Vanrobaeys, Mia De Herdt, Peter Ducatelle, Richard Devriese, Luc A. Typhlitis Caused by Intestinal Serpulina-Like Bacteria in Domestic Guinea Pigs (Cavia porcellus)